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Camostat mesilate

CAS No. 59721-29-8

Camostat mesilate( Foipan | FOY 305 )

Catalog No. M15218 CAS No. 59721-29-8

Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 59 In Stock
50MG 80 In Stock
100MG 113 In Stock
200MG 167 In Stock
500MG 282 In Stock
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Biological Information

  • Product Name
    Camostat mesilate
  • Note
    Research use only, not for human use.
  • Brief Description
    Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
  • Description
    Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
  • In Vitro
    ——
  • In Vivo
    Animal Model:6-8 week old female BALB/c mice (lethal SARS-CoV infection model)Dosage:30 mg/kg Administration:P.o.; twice a day for 9 days Result:Effective in protecting mice against death due to a lethal infection by SARS-CoV, with a survival rate of ～60%.
  • Synonyms
    Foipan | FOY 305
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    epithelial sodium channel (ENaC)
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    59721-29-8
  • Formula Weight
    494.52
  • Molecular Formula
    C21H26N4O8S
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 10 mg/mL (20.22 mM); DMSO: 99 mg/mL (200.19 mM)
  • SMILES
    CS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(C=C2)N=C(N)N)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Coote K, et al. J Pharmacol Exp Ther, 2009, 329(2), 764-774.
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